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Two master thieves (Brosnan and Hayek) are finally retiring after one last succesful mission. Residing in their own tropical paradise, their old nemesis, FBI Agent Stan P. Lloyd shows up to make sure they really are retired. Docked in the port is an ocean liner called the "Diamond Cruise" and Stan is convinced that they're not really retired at all, and that this is the next set up.
Twenty-eight days after a killer virus was accidentally unleashed from a British research facility, a small group of London survivors are caught in a desperate struggle to protect themselves from the infected. Carried by animals and humans, the virus turns those it infects into homicidal maniacs -- and it's absolutely impossible to contain.
Captain Barbossa, long believed to be dead, has come back to life and is headed to the edge of the Earth with Will Turner and Elizabeth Swann. But nothing is quite as it seems.
Captain Jack Sparrow works his way out of a blood debt with the ghostly Davey Jones, he also attempts to avoid eternal damnation.